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Contained use of GMOs and pathogens
(Last revised: July 9, 2010 )----------------------------------------------------------------------------------

Tools for risk assessment and risk management
Application of the Contained Use Legislation

* Certification and exemption: In French - In Dutch

* Scope of the legislation for the contained use of pathogenic organisms : In French - In Dutch

Biological Risk Assessment

* Criteria for the classification of GMM into class of risk 1: In French - In Dutch

* Criteria for the classification of transgenic animals into class of risk 1: in French - In Dutch

* Criteria for the classification of transgenic plants into class of risk 1: In French - In Dutch

* Risks associated to the use of viral vectors, inserts or cell cultures: In French - In Dutch

* Belgian classifications for micro-organisms (link)

* International classifications schemes for micro-organisms (link)

Risk Assessment, Biosafety Recommendations and Protective measures

* Animal cell cultures (link)

* Severe Acute Respiratory Syndrome (SARS) Coronavirus (link)

* Flow cytometry (link)

* Contained Use of M. tuberculosis Complex Isolates (PDF 264 kb)

* Guidelines for Clinical Laboratories: In French - In Dutch Updated for M. tuberculosis

* Biological Risk Assessment sheets: Practical examples of risk Assessement and Biosafety Recommendations for the Contained Use of Genetically Modified (Micro-)Organisms (link)

* Risk assessment of laboratories involving the manipulation of unconventional agents causing TSE (PDF 444 kb)

* Lentiviral vectors: Risk assessment and biosafety recommendations (Open-access review -PDF)

Risk Management and Technical notes

* Containment criteria and other protective measures: In French - In Dutch

* Biological Safety Cabinets: In French - In Dutch

* Negative air pressure in the L3 laboratories: In French - In Dutch (PDF 2.1 MB)

* Biological waste treatment and inactivation methods: In Dutch - In French (PDF 628 KB)

* Respiratory protection (contained use of GMOs and/or pathogens): In Dutch - In French (links)

Web Resources
* Biosafety in the laboratory and Risk assessment (link)
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