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Gene therapy clinical trials in Belgium
(Authors: M. Sneyers and M. Goossens - Last revised:
January 16, 2012
)
Since March 1996, 26 gene therapy protocols have been assessed in Belgium (Table 1).
Twenty-one of these protocols were multicenter. All trials were to be carried out in academic hospitals and notified for "contained uses of genetically modified micro-organisms". Eight protocols were also notified for "deliberate release of genetically modified micro-organisms for research and development purposes".
Table 2 illustrates the most relevant clinical data of the trials. Most protocols aimed at cancer therapy. Sixteen of them used viral vectors.
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