Molecular characterisation of the genetic maps
of commercial genetically modified plants
Prior to deliberate release of a GMO on the market under Part C of the Directive 2001/18/EC, information on the molecular data of the GMO as requested in Annex IIIB of the Directive should be given. This information is the basis for identifying any potential harmful characteristics (potential hazards) of the GMO. Most of the identifiable hazards which may cause adverse effects will be related to the gene(s) of interest. Additional adverse effects might be generated as a result of the method used to create the GMO and of the location of the construction in the genome of the GMO where the transgenes were inserted.
In March 2000, the company Monsanto submitted additional molecular data concerning the dossier Roundup Ready (RR) soybean (C/UK/94/M3/1) on the event GTS 40-3-2 to the UK authority. Namely a fragment of 250 bp adjacent to the 3 end of the primary functional insert, together with a small non-functional fragment of 72 bp segregating with the primary insert were disclosed. As a consequence of this discovery, the Competent Authorities of Belgium asked the CLO (Agricultural Research Centre, Melle, Belgium) to re-evaluate the molecular data of commercial GMOs. Their research results together with data provided by different scientific institutions, namely JRC (Joint Research Centre, Ispra, Italy), TEPRAL (Strasbourg, France) and INRA (Institut National de la Recherche Agronomique, Versailles, France), and found in publications were discussed during the meetings of the Belgian Biosafety Advisory Council on 6 December 2002 and 17 February 2003.
Overview of molecular characterisation of commercial GMOs
An overview of the molecular data of the events Bt11 maize, Bt176 maize, GTS 40-3-2 soybean, Mon810 maize, Ms8xRf3 oilseed rape and T25 maize, presented during the meetings of the Biosafety Adivisory Council can be found on this webpage. For reasons of confidentiality the annexes and figures are omitted from the reports. Full reports are available hereunder as pdf files: