| 
            ADP-0055-001           | 
                  
            A phase I, ascending dose, to evaluate safety and efficacy of ADP A2M4CD8 in HLA-A2+ patients with MAGE-A4 psoitives tumors           | 
                  
                  
            Humans           | 
                  
            MAGE-A4 specific T cell receptor (TCR) with a CD8α co-receptor             | 
              
          
                  | 
            Only notified under the "contained use" procedure. Dossier submitted on 21/02/2018.           | 
                  
            Efficacy and safety of bilateral intravitreal injection of GS010: a randomized, double-masked, placebo-controlled trial in subjects affected with G11778A ND4 leber hereditary optic neuropathy for up to one year.           | 
                  
                  
            Humans           | 
                  
            human wild-type MT-NDA (mitochondrial NADH Dehydrogenase 4)           | 
              
          
                  | 
            Only notified under the "contained use" procedure. Dossier submitted on 26/03/1998.           | 
                  
            Pilot study of immunization with recombinant canarypox virus vCP1469A expressing the MAGE-1.A1 and MAGE-3.A1 cytolytic T lymphocytes epitopes in patients with malignant melanoma, non-small cell lung carcinoma, head-and-neck squamous cell carcinoma, esopha           | 
                  
                  
            Humans           | 
                  
            HLA-A1 restricted CTL epitope of MAGE-1 and
MAGE-3 genes            |