A Phase 1b Multicenter, Open-label, Study of JNJ-90009530, an Autologous Anti-CD20 CAR-T Cell Therapy in Adult Participants with Relapsed or Refractory B-cell Non-

Study title: 
A Phase 1b Multicenter, Open-label, Study of JNJ-90009530, an Autologous Anti-CD20 CAR-T Cell Therapy in Adult Participants with Relapsed or Refractory B-cell Non-
Long title: 
A Phase 1b Multicenter, Open-label, Study of JNJ-90009530, an Autologous Anti-CD20 CAR-T Cell Therapy in Adult Participants with Relapsed or Refractory B-cell Non-
Date receipt dossier: 
1 Mar 2024
EudraCT number: 
2023-506259-97
Pharmaceutical study code: 
JNJ-90009530
Company / Sponsor: 
Janssen-Cilag International NV
Phase: 
Ib
Treated organism: 
Humans
Indication category: 
Cancer therapy
Disease: 
Relapsed or refractory B cell non-Hodgkin lymphoma
Therapeutic approach: 
Immunotherapy
Genetic modification: 
CD20 CAR
Method of transfer of nucleic acid of interest: 
Lentiviral vector
Administered biological material: 
Autologous T cells transduced with lentiviral vectors expressing CD20-CAR
Route of administration: 
Intravenous
Locations in Belgium: 
UZ Gent
Type of procedure: 
Contained use only
Current status: 
Authorized